D-Dimer Clinical test reference range: 0-0.55 mg/L

Influencing factors:

The following substances will interfere with the detection of the INNOVANCE* D-Dimer method at concentrations above those listed in the table below: Triglycerides (400 mg/dL) Hemolysis (200 mg/dL) Jaundice (60 mg/dL). Patient samples may contain heterophilic antibodies that may react in immunoassays and cause falsely elevated or depressed results. This assay is designed to minimize interference from heterophilic antibodies. However, it is impossible to ensure that all interferences are completely excluded from patient specimens. INNOVANCE*D-Dimer test results may be normal in patients with occult/micropulmonary embolism or distal deep vein thrombosis.

Clinical significance:

D-Dimer is a specific degradation product of cross-linked fibrin (Fib), and its production or increase reflects the activation of the coagulation and fibrinolytic systems. D-Dimer is a characteristic product of the degradation of cross-linked fibrin. It is increased in deep vein thrombosis, mass intravascular coagulation, myocardial infarction, severe hepatitis, tumors and other diseases. It is also increased to varying degrees after pregnancy and surgery. . It can also be used as an observation indicator of the effectiveness of thrombolytic treatment and a reliable marker of secondary fibrinolysis, used to identify primary fibrinolysis and secondary fibrinolysis.

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